Structure-Guided Design of AMP Mimics That Inhibit Fructose-1,6-bisphosphatase with High Affinity and Specificity

Author:

Erion Mark D.1,Dang Qun1,Reddy M. Rami1,Kasibhatla Srinivas Rao1,Huang Jingwei1,Lipscomb William N.1,van Poelje Paul D.1

Affiliation:

1. Contribution from the Departments of Medicinal Chemistry, Biochemistry, and Molecular Modeling, Metabasis Therapeutics, Inc., 11119 North Torrey Pines Road, La Jolla, California 92037, and Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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