An Orally Bioavailable Pyrrolinone Inhibitor of HIV-1 Protease: Computational Analysis and X-ray Crystal Structure of the Enzyme Complex-Reference-Cited by-同舟云学术

An Orally Bioavailable Pyrrolinone Inhibitor of HIV-1 Protease: Computational Analysis and X-ray Crystal Structure of the Enzyme Complex

Published:1997-08-01 Issue:16 Volume:40 Page:2440-2444
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Smith Amos B.,Hirschmann Ralph,Pasternak Alexander,Yao Wenquing,Sprengeler Paul A.,Holloway M. Katharine,Kuo Lawrence C.,Chen Zhongguo,Darke Paul L.,Schleif William A.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970195u

Reference31 articles.

1. The design and synthesis of 2,5-linked pyrrolinones. A potential non-peptide peptidomimetic scaffold

Cited by 71 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Characterization of structure of peptidyl-tRNA hydrolase from Enterococcus faecium and its inhibition by a pyrrolinone compound;International Journal of Biological Macromolecules;2024-08

2. Oligo-benzamide-based peptide mimicking tools for modulating biology;Methods in Enzymology;2024

3. Synthesis of Highly Substituted Pyrrolo[1,2‐a]quinoline‐3,5‐diones through Ag(I) Catalyzed Cyclization of 4‐Hydroxyquinolinyl‐2‐ynones;European Journal of Organic Chemistry;2023-11-13

4. Recent Advances in Organocatalyzed Asymmetric Sulfa‐Michael Addition Triggered Cascade Reactions;The Chemical Record;2023-01-03

5. Tandem annulation and 1,2-alkyl migration reactions of α-bromo-β-oxoamides and amines: Access to polysubstituted pyrrolin-4-ones;Tetrahedron;2022-04