Improved Asymmetric Synthesis of 3,4-Dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)phenyl]-α-(trifluoromethyl)-1(2H)-quinolineethanol, a Potent Cholesteryl Ester Transfer Protein Inhibitor-Reference-Cited by-同舟云学术

Improved Asymmetric Synthesis of 3,4-Dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)phenyl]-α-(trifluoromethyl)-1(2H)-quinolineethanol, a Potent Cholesteryl Ester Transfer Protein Inhibitor

Published:2009-06-09 Issue:13 Volume:11 Page:2812-2815
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Rano Thomas A.¹,Kuo Gee-Hong¹

Affiliation:

1. Johnson & Johnson Pharmaceutical Research & Development, L.L.C.,1000 Route 202, P.O. Box 300, Raritan, New Jersey 08869

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol900639j

Reference23 articles.

1. Plasma cholesteryl ester transfer protein

2. New approaches to atherosclerosis: An overview

3. For an excellent review of CETP inhibitors, see:

4. Oral Cholesteryl Ester Transfer Protein (CETP) Inhibitors: A Potential New Approach for Treating Coronary Artery Disease

5. Effects of Torcetrapib in Patients at High Risk for Coronary Events

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