Shooting for Selective Druglike G-Quadruplex Binders: Evidence for Telomeric DNA Damage and Tumor Cell Death

Author:

Cosconati Sandro1,Rizzo Angela2,Trotta Roberta3,Pagano Bruno3,Iachettini Sara2,De Tito Stefano3,Lauri Ilaria3,Fotticchia Iolanda4,Giustiniano Mariateresa3,Marinelli Luciana3,Giancola Concetta4,Novellino Ettore3,Biroccio Annamaria2,Randazzo Antonio3

Affiliation:

1. Dipartimento di Scienze Ambientali, Seconda Università di Napoli, 81100 Caserta, Italy

2. Experimental Chemotherapy Laboratory, Regina Elena National Cancer Institute, 00158 Rome, Italy

3. Dipartimento di Chimica Farmaceutica e Tossicologica, Università di Napoli “Federico II”, 80131 Napoli, Italy

4. Dipartimento di Scienze Chimiche, Università di Napoli “Federico II”, 80126, Naples, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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