Discovery of Novel Gain-of-Function Mutations Guided by Structure-Based Deep Learning-Reference-Cited by-同舟云学术

Discovery of Novel Gain-of-Function Mutations Guided by Structure-Based Deep Learning

Published:2020-10-16 Issue:11 Volume:9 Page:2927-2935
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Shroff Raghav¹^ORCID,Cole Austin W.¹^ORCID,Diaz Daniel J.²,Morrow Barrett R.¹,Donnell Isaac¹,Annapareddy Ankur³,Gollihar Jimmy³,Ellington Andrew D.¹^ORCID,Thyer Ross¹^ORCID

Affiliation:

1. Center for Systems and Synthetic Biology, The Department of Molecular Biosciences, The University of Texas at Austin, Austin, Texas 78712, United States

2. The Department of Chemistry, The University of Texas at Austin, Austin, Texas 78712, United States

3. US Army Research Laboratories − South, 2506 Speedway, Austin, Texas 78712, United States

Funder

Welch Foundation

Army Research Office

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.0c00345