Development of CRISPR/Cas9-Based Genome Editing Tools for Polyploid Yeast Cyberlindnera jadinii and Its Application in Engineering Heterologous Steroid-Producing Strains

Author:

Gu Lishan1,Zhang Rongxin1,Fan Xuqian2,Wang Yu3,Ma Kaiyu4,Jiang Jingjing3,Li Gen2,Wang Honglei1,Fan Feiyu2ORCID,Zhang Xueli2ORCID

Affiliation:

1. College of Chemistry and Life Science, Changchun University of Technology, 2055 Yanan Street, Changchun 130012, P. R. China

2. Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, 32 West Seventh Avenue, Tianjin Airport Economic Area, Tianjin 300308, P. R. China

3. College of Biotechnology and Food Science, Tianjin University of Commerce, 409 Glorious Road, Beichen District, Tianjin 300134, P. R. China

4. College of Biotechnology, Tianjin University of Science and Technology, No. 29 of 13th Avenue, TEDA, Tianjin 300457, P. R. China

Funder

National Key Research and Development Program of China

National Science Fund for Distinguished Young Scholars

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

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