Targeted Cancer Cell Killing by Highly Selective miRNA-Triggered Activation of a Prokaryotic Toxin–Antitoxin System-Reference-Cited by-同舟云学术

Targeted Cancer Cell Killing by Highly Selective miRNA-Triggered Activation of a Prokaryotic Toxin–Antitoxin System

Published:2019-07-26 Issue:8 Volume:8 Page:1730-1736
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Turnbull Alice¹,Bermejo-Rodríguez Camino¹,Preston Mark A.¹,Garrido-Barros María²³,Pimentel Belén¹²³,de la Cueva-Méndez Guillermo¹²³^ORCID

Affiliation:

1. MRC Cancer Cell Unit, Hutchison/MRC Research Centre, Hills Road, Cambridge CB2 0XZ, U.K.

2. Synthetic Biology and Smart Therapeutic Nanosystems Laboratory, Andalusian Centre for Nanomedicine and Biotechnology−BIONAND, 29590 Málaga, Spain

3. Nanobioengineering of Smart Therapeutic and Diagnostic Systems Laboratory, Area of Oncology and Oncohematology, Instituto de Investigación Biomédica de Málaga−IBIMA, 29010 Málaga, Spain

Funder

Medical Research Council

Consejer?a de Salud, Junta de Andaluc?a

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.9b00172

Reference36 articles.

1. Toxin-Antitoxin Systems in Bacteria and Archaea

2. Toxins-antitoxins: diversity, evolution and function

3. Toxin-antitoxins and bacterial virulence

4. Kid cleaves specific mRNAs at UUACU sites to rescue the copy number of plasmid R1

5. Gene and cell survival: lessons from prokaryotic plasmid R1

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