Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination-Reference-Cited by-同舟云学术

Carving out a Glycoside Hydrolase Active Site for Incorporation into a New Protein Scaffold Using Deep Network Hallucination

Published:2024-02-15 Issue:3 Volume:13 Page:862-875
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Hansen Anders Lønstrup¹,Theisen Frederik Friis¹^ORCID,Crehuet Ramon²^ORCID,Marcos Enrique³,Aghajari Nushin⁴^ORCID,Willemoës Martin¹^ORCID

Affiliation:

1. The Linderstrøm-Lang Centre for Protein Science, Section for Biomolecular Sciences, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark

2. Institute for Advanced Chemistry of Catalonia (IQAC), CSIC, Carrer Jordi Girona 18-26, 08034 Barcelona, Spain

3. Protein Design and Modeling Lab, Department of Structural and Molecular Biology, Molecular Biology Institute of Barcelona (IBMB), CSIC, Baldiri Reixac 10, 08028 Barcelona, Spain

4. Molecular Microbiology and Structural Biochemistry, CNRS, University of Lyon1, UMR5086, 7 Passage du Vercors, F-69367 Lyon CEDEX 07, France

Funder

Novo Nordisk

Ministerio de Ciencia e Innovaci?n

Danmarks Frie Forskningsfond

Ag?ncia de Gesti? d'Ajuts Universitaris i de Recerca

Centre National de la Recherche Scientifique

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.3c00674

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