Biosynthesis of Novel Statins by Combining Heterologous Genes from Xylaria and Aspergillus-Reference-Cited by-同舟云学术

Biosynthesis of Novel Statins by Combining Heterologous Genes from Xylaria and Aspergillus

Published:2018-11-07 Issue:12 Volume:7 Page:2783-2789
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Itoh Hiroya¹²,Matsui Makoto¹²,Miyamura Yuki²,Takeda Itaru³,Ishii Jun²⁴^ORCID,Kumagai Toshitaka²⁵,Machida Masayuki²³,Shibata Takashi¹²,Arita Masanori²⁶⁷^ORCID

Affiliation:

1. Biotechnology Laboratories, Astellas Pharma Inc., Tokodai 5-2-3, Tsukuba, Ibaraki 300-2635, Japan

2. Technology Research Association of Highly Efficient Gene Design (TRAHED), Tsukisamu-Higashi 2-17-2-1, Toyohira, Sapporo, Hokkaido 062-8517, Japan

3. Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukisamu-Higashi 2-17-2-1, Toyohira, Sapporo, Hokkaido 062-8517, Japan

4. Engineering Biology Research Center, Kobe University, Rokkodai 1-1, Nada, Kobe, Hyogo 657-8501, Japan

5. Fermlab Inc., Shirakawa 4-3-1-913, Koto, Tokyo 135-0021, Japan

6. RIKEN Center for Sustainable Resource Science, Suehiro 1-7-22, Tsurumi, Yokohama, Kanagawa 230-0045, Japan

7. National Institute of Genetics, Yata 1111, Mishima, Shizuoka 411-8540, Japan

Funder

Ministry of Economy, Trade and Industry

Japan Society for the Promotion of Science

National Bioscience Database Center

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acssynbio.8b00392

Reference19 articles.

1. ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum.

2. Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update

3. A historical perspective on the discovery of statins

4. Structural Mechanism for Statin Inhibition of HMG-CoA Reductase

5. FR901512, a Novel HMG-CoA Reductase Inhibitor Produced by an Agonomycetous Fungus No. 14919: I. Taxonomy of the Producing Organism, Fermentation, Isolation and Physico-chemical Properties

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