A BioBricks Metabolic Engineering Platform for the Biosynthesis of Anthracyclinones in <i>Streptomyces coelicolor</i>-Reference-Cited by-同舟云学术

A BioBricks Metabolic Engineering Platform for the Biosynthesis of Anthracyclinones in Streptomyces coelicolor

Published:2022-11-15 Issue:12 Volume:11 Page:4193-4209
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Wang Rongbin¹,Nguyen Jennifer²^ORCID,Hecht Jacob²,Schwartz Nora²,Brown Katelyn V.²,Ponomareva Larissa V.,Niemczura Magdalena¹,van Dissel Dino³⁴,van Wezel Gilles P.³^ORCID,Thorson Jon S.^ORCID,Metsä-Ketelä Mikko¹^ORCID,Shaaban Khaled A.^ORCID,Nybo S. Eric²^ORCID

Affiliation:

1. Department of Life Technologies, University of Turku, FIN-20014 Turku, Finland

2. Department of Pharmaceutical Sciences, College of Pharmacy, Ferris State University, Big Rapids, Michigan 49307, United States

3. Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE Leiden, The Netherlands

4. Department of Biotechnology and Nanomedicine, SINTEF AS, P.O. Box 4760 Torgarden, NO-7465 Trondheim, Norway

Funder

U.S. Department of Health and Human Services

European Research Council

Turun YliopistosÃ¤Ã¤tiÃ¶

University of Kentucky

Novo Nordisk Fonden

Academy of Finland

China Scholarship Council

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.2c00498

Reference90 articles.

1. Anthracyclines: biosynthesis, engineering and clinical applications

2. Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin

3. Minimal Streptomyces sp. strain C5 daunorubicin polyketide biosynthesis genes required for aklanonic acid biosynthesis

4. Characterization of the Streptomyces peucetius ATCC 29050 genes encoding doxorubicin polyketide synthase

5. The entire nogalamycin biosynthetic gene cluster of Streptomyces nogalater: characterization of a 20-kb DNA region and generation of hybrid structures

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