A Small-Molecule Inducible Synthetic Circuit for Control of the SOS Gene Network without DNA Damage-Reference-Cited by-同舟云学术

A Small-Molecule Inducible Synthetic Circuit for Control of the SOS Gene Network without DNA Damage

Published:2017-09-01 Issue:11 Volume:6 Page:2067-2076
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Kubiak Jeffrey M.¹^ORCID,Culyba Matthew J.¹,Liu Monica Yun¹,Mo Charlie Y.¹,Goulian Mark²,Kohli Rahul M.¹^ORCID

Affiliation:

1. Department of Medicine, Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

2. Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

Funder

Burroughs Wellcome Fund

National Institute of General Medical Sciences

Edward Mallinckrodt, Jr. Foundation

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acssynbio.7b00108

Reference50 articles.

1. The bacterial LexA transcriptional repressor

2. DNA binding properties of the LexA repressor

3. Regulation of Bacterial RecA Protein Function

4. Mechanism of specific LexA cleavage: Autodigestion and the role of RecA coprotease

5. LexA Repressor Forms Stable Dimers in Solution

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