Protein-Specific Signal Peptides for Mammalian Vector Engineering-Reference-Cited by-同舟云学术

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Protein-Specific Signal Peptides for Mammalian Vector Engineering

Published:2023-07-24 Issue:8 Volume:12 Page:2339-2352
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

O’Neill Pamela¹^ORCID,Mistry Rajesh K.²,Brown Adam J.¹³,James David C.¹³

Affiliation:

1. Department of Chemical and Biological Engineering, University of Sheffield, Mappin Street, Sheffield S1 3JD, U.K.

2. AstraZeneca, BioPharmaceutical Development, Cell Culture and Fermentation Sciences, Aaron Klugg Building, Granta Park, Cambridge CB21 6GH, U.K.

3. SynGenSys Limited, Freeths LLP, Norfolk Street, Sheffield S1 2JE, U.K.

Funder

AstraZeneca

Biotechnology and Biological Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.3c00157

Reference42 articles.

1. Biopharmaceutical benchmarks 2022

2. Production of recombinant protein therapeutics in cultivated mammalian cells

3. CHO genome mining for synthetic promoter design

4. mRNA stability and antibody production in CHO cells: Improvement through gene optimization

5. Design of Experiment in CHO and HEK transient transfection condition optimization

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1. Simple improvements in vector design afford substantial gains in AAV delivery of aggregation-slowing Aβ variants;Molecular Therapy - Nucleic Acids;2024-12

2. Selective delivery of imaging probes and therapeutics to the endoplasmic reticulum or Golgi apparatus: Current strategies and beyond;Advanced Drug Delivery Reviews;2024-09

3. Large-Scale Comparative Transcriptomic Analysis of CHO Cell Functional Adaptation to Recombinant Monoclonal Antibody Production;2024-07-01

4. Episomal Vectors for Stable Production of Recombinant Proteins and Engineered Antibodies;Antibodies;2024-03-11

5. Manipulating gene expression levels in mammalian cell factories: An outline of synthetic molecular toolboxes to achieve multiplexed control;New Biotechnology;2024-03

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