Repurposing the Homing Endonuclease I-SceI for Positive Selection and Development of Gene-Editing Technologies

Author:

Lee Kok Zhi1,Mechikoff Michael A.1,Parasa Mrugesh Krishna23,Rankin Tyler J.4,Pandolfi Paula4,Fitzgerald Kevin S.1,Hillman Ethan T.15,Solomon Kevin V.1356ORCID

Affiliation:

1. Department of Agricultural and Biological Engineering, Purdue University, 225 South University Street, West Lafayette, Indiana 47907-2093, United States

2. Weldon School of Biomedical Engineering, Purdue University, 206 S Martin Jischke Drive, West Lafayette, Indiana 47907-2093, United States

3. Department of Chemical & Biomolecular Engineering, University of Delaware, 150 Academy Street, Newark, Delaware 19716, United States

4. Department of Biological Sciences, Purdue University, 915 West State Street, West Lafayette, Indiana 47907-2054, United States

5. Purdue University Interdisciplinary Life Science Program (PULSe), Purdue University, 155 South Grant Street, West Lafayette, Indiana 47907, United States

6. Laboratory of Renewable Resources Engineering (LORRE), Purdue University, 500 Central Drive, West Lafayette, Indiana 47907-2022, United States

Funder

National Institute of Food and Agriculture

Purdue Research Foundation

Ralph W. and Grace M. Showalter Research Trust Fund

Colleges of Engineering and Agriculture, Purdue University

College of Engineering, University of Delaware

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

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