Switchable CAR-T Cells Outperformed Traditional Antibody-Redirected Therapeutics Targeting Breast Cancers

Author:

Cao Yu J.1ORCID,Wang Xuechun1,Wang Zhidong1,Zhao Lijun1,Li Shuhong1,Zhang Zhuxia1,Wei Xiaoyi1,Yun Hwayoung2ORCID,Choi Sei-hyun3,Liu Zhong4,Zhao Lili5,Kazane Stephanie A.6

Affiliation:

1. State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, Guangdong 518055, China

2. College of Pharmacy, Pusan National University, Busan 46241, Republic of Korea

3. Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States

4. Shandong New Time Pharmaceutical Co., Ltd, No. 1 North Outer Ring Road, Feixian County, Shandong 273400, China

5. State Engineering Laboratory of High Expression of Mammalian Cells, No. 1 North Outer Ring Road, Feixian County, Shandong 273400, China

6. California Institute for Biomedical Research, 11119 North Torrey Pines Road, La Jolla, California 92037, United States

Funder

National Natural Science Foundation of China

Guangdong Natural Science Foundation

Shenzhen Science and Technology Innovation Program

National Key R&D Program of China

The Key Research and Development of Program of Shandong Province

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

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