Receptor Elimination by E3 Ubiquitin Ligase Recruitment (REULR): A Targeted Protein Degradation Toolbox-Reference-Cited by-同舟云学术

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Receptor Elimination by E3 Ubiquitin Ligase Recruitment (REULR): A Targeted Protein Degradation Toolbox

Published:2023-04-03 Issue:4 Volume:12 Page:1081-1093
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Siepe Dirk H.¹^ORCID,Picton Lora K.¹,Garcia K. Christopher¹²³^ORCID

Affiliation:

1. Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California 94305, United States

2. Department of Structural Biology, Stanford University School of Medicine, Stanford, California 94305, United States

3. Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, United States

Funder

Howard Hughes Medical Institute

National Cancer Institute

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.2c00587

Reference67 articles.

1. First targeted protein degrader hits the clinic

2. Protacs: Chimeric molecules that target proteins to the Skp1-Cullin-F box complex for ubiquitination and degradation

3. Prime time for PROTACs

4. PROTAC targeted protein degraders: the past is prologue

5. Molecular Glues for Targeted Protein Degradation: From Serendipity to Rational Discovery

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