GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries-Reference-Cited by-同舟云学术

GeneORator: An Effective Strategy for Navigating Protein Sequence Space More Efficiently through Boolean OR-Type DNA Libraries

Published:2019-05-27 Issue:6 Volume:8 Page:1371-1378
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Currin Andrew¹²^ORCID,Kwok Jane²,Sadler Joanna C.²,Bell Elizabeth L.³,Swainston Neil¹²^ORCID,Ababi Maria³⁴,Day Philip³,Turner Nicholas J.¹²^ORCID,Kell Douglas B.¹²

Affiliation:

1. Manchester Centre for Synthetic Biology of Fine and Speciality Chemicals (SYNBIOCHEM), Manchester Institute of Biotechnology, The University of Manchester, Manchester M1 7DN, United Kingdom

2. School of Chemistry, The University of Manchester, Manchester M13 9PL, United Kingdom

3. Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PL, United Kingdom

4. School of Computer Science, The University of Manchester, Manchester M13 9PL, United Kingdom

Funder

Biotechnology and Biological Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acssynbio.9b00063

Reference69 articles.

1. Directed evolution: Past, present, and future

2. Rational evolutionary design: The theory of in vitro protein evolution

3. Fancy footwork in the sequence space shuffle

4. Protein Design by Directed Evolution

5. Directed evolution drives the next generation of biocatalysts

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