Evaluation of a Series of Naphthamides as Potent, Orally Active Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinase Inhibitors-Reference-Cited by-同舟云学术

Evaluation of a Series of Naphthamides as Potent, Orally Active Vascular Endothelial Growth Factor Receptor-2 Tyrosine Kinase Inhibitors

Published:2008-03-01 Issue:6 Volume:51 Page:1668-1680
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Weiss Matthew M.¹,Harmange Jean-Christophe¹,Polverino Anthony J.¹,Bauer David¹,Berry Loren¹,Berry Virginia¹,Borg George¹,Bready James¹,Chen Danlin¹,Choquette Deborah¹,Coxon Angela¹,DeMelfi Tom¹,Doerr Nicholas¹,Estrada Juan¹,Flynn Julie¹,Graceffa Russell F.¹,Harriman Shawn P.¹,Kaufman Stephen¹,La Daniel S.¹,Long Alexander¹,Neervannan Sesha¹,Patel Vinod F.¹,Potashman Michele¹,Regal Kelly¹,Roveto Phillip M.¹,Schrag Michael L.¹,Starnes Charlie¹,Tasker Andrew¹,Teffera Yohannes¹,Whittington Douglas A.¹,Zanon Roger¹

Affiliation:

1. Department of Medicinal Chemistry, Department of Molecular Structure, and Department of Pharmacokinetics and Drug Metabolism, Amgen Inc., One Kendall Square, Building 1000, Cambridge, Massachusetts 02139, and Department of Oncology Research, Department of Toxicology, and Department of Pharmaceutics, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm701098w

Reference44 articles.

1. Anti-Angiogenesis

2. VEGF and the quest for tumour angiogenesis factors

3. New paradigms for the treatment of cancer: The role of anti-angiogenesis agents

4. Vascular-targeting therapies for treatment of malignant disease

5. Mechanisms of angiogenesis and arteriogenesis

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