8-[4-[2-(1,2,3,4-Tetrahydroisoquinolinyl)]butyl]-8-azaspiro[4.5]decane-7,9-dione: A New 5-HT1A Receptor Ligand with the Same Activity Profile as Buspirone-Reference-Cited by-同舟云学术

8-[4-[2-(1,2,3,4-Tetrahydroisoquinolinyl)]butyl]-8-azaspiro[4.5]decane-7,9-dione: A New 5-HT1A Receptor Ligand with the Same Activity Profile as Buspirone

Published:1996-01-01 Issue:5 Volume:39 Page:1125-1129
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mokrosz Jerzy L.¹,Dereń-Wesołek Anna¹,Tatarczyńska Ewa¹,Duszyńska Beata¹,Bojarski Andrzej J.¹,Mokrosz Maria J.¹,Chojnacka-Wójcik Ewa¹

Affiliation:

1. Departments of Medicinal Chemistry and New Drugs, Institute of Pharmacology, Polish Academy of Sciences, 12 Smȩtna Street, 31-343 Kraków, Poland

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm950662c

Reference36 articles.

1. Effects of Non-Narcotic Analgesics on the Liver

2. Differential effects of 5-hydroxytryptamine1A selective drugs on the 5-HT behavioral syndrome

3. Novel anxiolytics discriminate between postsynaptic serotonin receptors mediating different physiological responses on single neurons of the rat hippocampus

4. 5-HT1A receptor-related anxiolytics

5. Anticonflict effect of ipsapirone, buspirone and gepirone is not mediated by their common metabolite 1-(2-pyrimidinyl)piperazine

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