β-Glucuronidase-Cleavable Prodrugs of O6-Benzylguanine and O6-Benzyl-2‘-deoxyguanosine-Reference-Cited by-同舟云学术

β-Glucuronidase-Cleavable Prodrugs of O6-Benzylguanine and O6-Benzyl-2‘-deoxyguanosine

Published:2004-12-13 Issue:1 Volume:48 Page:256-261
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wei Guangping¹,Loktionova Natalia A.¹,Pegg Anthony E.¹,Moschel Robert C.¹

Affiliation:

1. Laboratory of Comparative Carcinogenesis, National Cancer Institute at Frederick, PO Box B, Bldg. 538, Frederick, Maryland 21702, and Departments of Cellular and Molecular Physiology and Pharmacology, The Pennsylvania State University College of Medicine, PO Box 850, Hershey, Pennsylvania 17033

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0493865

Reference33 articles.

1. Rationale for Design of Biologically Reversible Drug Derivatives: Prodrugs

2. Prodrugs and site-specific drug delivery

3. Antibody directed enzymes revive anti-cancer prodrugs concept

4. A cytotoxic agent can be generated selectively at cancer sites

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