Vascular Physiology and Protein Disposition in a Preclinical Model of Neurodegeneration
Author:
Affiliation:
1. Preclinical and Translational Pharmacokinetics and ‡In Vivo Studies, Non-Clinical Operations, Genentech Research and Early Development, South San Francisco, California 94080, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp3004786
Reference54 articles.
1. The basics of preclinical drug development for neurodegenerative disease indications
2. Motor Neuron Degeneration in Mice that Express a Human Cu,Zn Superoxide Dismutase Mutation
3. Age-Dependent Penetrance of Disease in a Transgenic Mouse Model of Familial Amyotrophic Lateral Sclerosis
4. Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions.
5. Selective vulnerability and pruning of phasic motoneuron axons in motoneuron disease alleviated by CNTF
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