Lab-Scale Preparation of a Novel Cyclopenta[b]furan Chemokine Receptor Antagonist

Author:

Teleha Christopher A.,Branum Shawn,Zhang Yongzheng,Reuman Michael E.,Van Der Steen Luc1,Verbeek Marc1,Fawzy Nagy,Leo Gregory C.,Winters Michael P.,Kang Fu-An,Kolpak Michael,Beauchamp Derek A.,Lanter James C.,Russell Ronald K.,Sui Zhihua,Vanbaelen Hilde1

Affiliation:

1. Preparative Separation Techniques, API Small, Janssen Research and Development, 30 Turnhoutseweg, Beerse, B-2340, Belgium

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference29 articles.

1. The discovery and SAR of cyclopenta[b]furans as inhibitors of CCR2

2. Novel 2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists

3. Lab-Scale Preparation of a Novel Carbocyclic Chemokine Receptor Antagonist

4. a(a)Jensen, M.; Larsen, R.; Sidler, D. R.WO 2005044264, 2005.

5. bButora, G.; Guiadeen, D.; Kothandaraman, S.; Maccoss, M.; Mills, S. G.; Yang, L.WO 2005072361, 2005.

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