Alkylsulfanyl-1,2,4-triazoles, a New Class of Allosteric Valosine Containing Protein Inhibitors. Synthesis and Structure–Activity Relationships
Author:
Affiliation:
1. Nerviano Medical Sciences S.r.l., Oncology, Viale Pasteur 10, 20014 Nerviano (MI), Italy
2. Genentech Inc., 1 DNA Way, South San Francisco, California 94080, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm3013213
Reference28 articles.
1. AAA+superfamily ATPases: common structure-diverse function
2. Molecular perspectives on p97–VCP: progress in understanding its structure and diverse biological functions
3. Nucleotide Dependent Motion and Mechanism of Action of p97/VCP
4. Improved Structures of Full-Length p97, an AAA ATPase: Implications for Mechanisms of Nucleotide-Dependent Conformational Change
5. Targeted deletion of p97 (VCP/CDC48) in mouse results in early embryonic lethality
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