Toward Potent Ghrelin Receptor Ligands Based on Trisubstituted 1,2,4-Triazole Structure. 2. Synthesis and Pharmacological in Vitro and in Vivo Evaluations-Reference-Cited by-同舟云学术

Toward Potent Ghrelin Receptor Ligands Based on Trisubstituted 1,2,4-Triazole Structure. 2. Synthesis and Pharmacological in Vitro and in Vivo Evaluations

Published:2007-10-10 Issue:23 Volume:50 Page:5790-5806
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Moulin Aline¹,Demange Luc¹,Bergé Gilbert¹,Gagne Didier¹,Ryan Joanne¹,Mousseaux Delphine¹,Heitz Annie¹,Perrissoud Daniel¹,Locatelli Vittorio¹,Torsello Antonio¹,Galleyrand Jean-Claude¹,Fehrentz Jean-Alain¹,Martinez Jean¹

Affiliation:

1. Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS, Université Montpellier I et Université Montpellier II, BP 14491, Faculté de Pharmacie, 15 Avenue Charles Flahault, 34093 Montpellier Cedex 5, France, CBS, UMR 5048, 29 Rue de Navacelles, 34090 Montpellier, France, Zentaris GmbH, Weismuellerstrasse 50, 60314 Frankfurt am Main, Germany, and Department of Experimental Medicine, School of Medicine, University of Milano-Bicocca, Via Cadore 48, 20052 Monza (MI), Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0704550

Reference11 articles.

1. A Receptor in Pituitary and Hypothalamus That Functions in Growth Hormone Release

2. Ghrelin is a growth-hormone-releasing acylated peptide from stomach

3. Synthesis and Pharmacological in Vitro and in Vivo Evaluations of Novel Triazole Derivatives as Ligands of the Ghrelin Receptor. 1

4. Effect of growth hormone secretagogue LY444711 on IGF-1, growth hormone, and cortisol levels in beagle dogs after one and seven daily oral doses

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