Combining Experimental Evidence and Molecular Dynamic Simulations To Understand the Mechanism of Action of the Antimicrobial Octapeptide Jelleine-I

Author:

dos Santos Cabrera Marcia Perez12,Baldissera Gisele23,Silva-Gonçalves Laiz da Costa4,de Souza Bibiana Monson5,Riske Karin A.4,Palma Mario Sérgio5,Ruggiero José Roberto2,Arcisio-Miranda Manoel4

Affiliation:

1. Departamento de Química e Ciências Ambientais, Universidade Estadual Paulista, São José do Rio Preto, São Paulo 15054-000, Brazil

2. Departamento de Física, Universidade Estadual Paulista, São José do Rio Preto, São Paulo 15054-000, Brazil

3. Faculdade de Tecnologia de Catanduva, Catanduva, São Paulo 15800-200, Brazil

4. Departamento de Biofísica, Universidade Federal de São Paulo, São Paulo, São Paulo 04023-062, Brazil

5. Centro de Estudos de Insetos Sociais, Universidade Estadual Paulista, Rio Claro, São Paulo 13506-900, Brazil

Funder

São Paulo Research Foundation

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Reference35 articles.

1. How to cope with the quest for new antibiotics

2. Jelleines: a family of antimicrobial peptides from the Royal Jelly of honeybees (Apis mellifera)

3. Fontana, R. (2002) Caracterização molecular e functional de componentes antimicrobianos da geléia real deApis mellifera. PhD thesis, pp1–119, Universidade Estadual Paulista, Instituto de Biociencias de Rio Claro, SP, Brasil.

4. Insights into the mechanisms of action of host defence peptides from biophysical and structural investigations

5. Activity and selectivity of histidine-containing lytic peptides to antibiotic-resistant bacteria

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