Druggability Analysis and Structural Classification of Bromodomain Acetyl-lysine Binding Sites-Reference-Cited by-同舟云学术

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Druggability Analysis and Structural Classification of Bromodomain Acetyl-lysine Binding Sites

Published:2012-07-12 Issue:17 Volume:55 Page:7346-7359
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Vidler Lewis R.¹,Brown Nathan¹,Knapp Stefan²,Hoelder Swen¹

Affiliation:

1. Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, United Kingdom

2. Nuffield Department of Clinical Medicine, Structural Genomics Consortium, Oxford University, Old Road Campus Research Building, Headington, Oxford OX3 7DQ, United Kingdom

Funder

Wellcome Trust

GlaxoSmithKline

Pfizer

Takeda Pharmaceuticals North America

Canada Foundation for Innovation

Novartis

Canadian Institutes of Health Research

Cancer Research UK

Abbott Laboratories

National Institute for Health Research

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300346w

Reference41 articles.

1. Chromatin Modifications and Their Function

2. Translating the Histone Code

3. Bromodomain: an acetyl-lysine binding domain

4. Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

5. Structure and acetyl-lysine recognition of the bromodomain

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