Stereoelectronic Effect on One-Electron Reductive Release of 5-Fluorouracil from 5-Fluoro-1-(2‘-oxocycloalkyl)uracils as a New Class of Radiation-Activated Antitumor Prodrugs-Reference-Cited by-同舟云学术

Stereoelectronic Effect on One-Electron Reductive Release of 5-Fluorouracil from 5-Fluoro-1-(2‘-oxocycloalkyl)uracils as a New Class of Radiation-Activated Antitumor Prodrugs

Published:2000-07-01 Issue:15 Volume:65 Page:4641-4647
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Mori Mayuko¹,Hatta Hiroshi¹,Nishimoto Sei-ichi¹

Affiliation:

1. Department of Energy and Hydrocarbon Chemistry, Graduate School of Engineering, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo000245u

Reference33 articles.

1. 1-(5'-Fluoro-6'-hydroxy-5',6'-dihydrouracil-5'-yl)-5-fluorouracil, a novel N(1)-C(5)-linked dimer that releases 5-fluorouracil by radiation activation under hypoxic conditions

2. Fluorouracil: biochemistry and pharmacology.

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