Incorporation of Basic Side Chains into Cryptolepine Scaffold: Structure−Antimalarial Activity Relationships and Mechanistic Studies-Reference-Cited by-同舟云学术

Incorporation of Basic Side Chains into Cryptolepine Scaffold: Structure−Antimalarial Activity Relationships and Mechanistic Studies

Published:2011-01-05 Issue:3 Volume:54 Page:734-750
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Lavrado João¹,Cabal Ghislain G.²,Prudêncio Miguel²,Mota Maria M.²,Gut Jiri³,Rosenthal Philip J.³,Díaz Cecília⁴,Guedes Rita C.¹,dos Santos Daniel J. V. A.¹,Bichenkova Elena⁵,Douglas Kenneth T.⁵,Moreira Rui¹,Paulo Alexandra¹

Affiliation:

1. Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Faculty of Pharmacy, University of Lisbon. Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal

2. Unidade de Malária, Instituto de Medicina Molecular, Universidade de Lisboa, 1649-028 Lisboa, Portugal

3. Department of Medicine, San Francisco General Hospital, University of California, San Francisco, Box 0811, San Francisco, California 94143, United States

4. Departamento de Bioquímica, Escuela de Medicina and Instituto Clodomiro Picado, Universidad de Costa Rica, 2060 San José, Costa Rica

5. School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester M13 9PT, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101383f

Reference59 articles.

1. Malaria Combination Therapies: Advantages and Shortcomings

2. Recent highlights in antimalarial drug resistance and chemotherapy research

3. Medical need, scientific opportunity and the drive for antimalarial drugs