Extreme Multidrug Resistant HIV-1 Protease with 20 Mutations Is Resistant to Novel Protease Inhibitors with P1′-Pyrrolidinone or P2-Tris-tetrahydrofuran-Reference-Cited by-同舟云学术

Extreme Multidrug Resistant HIV-1 Protease with 20 Mutations Is Resistant to Novel Protease Inhibitors with P1′-Pyrrolidinone or P2-Tris-tetrahydrofuran

Published:2013-05-01 Issue:10 Volume:56 Page:4017-4027
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Agniswamy Johnson¹,Shen Chen-Hsiang¹,Wang Yuan-Fang¹,Ghosh Arun K.²,Rao Kalapala Venkateswara²,Xu Chun-Xiao²,Sayer Jane M.³,Louis John M.³,Weber Irene T.¹

Affiliation:

1. Department of Biology, Molecular Basis of Disease Program, Georgia State University, Atlanta, Georgia 30303, United States

2. Department of Chemistry and Medicinal Chemistry, Purdue University, West Lafayette, Indiana 47907, United States

3. Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, DHHS, Bethesda, Maryland 20892-0520, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400231v

Reference47 articles.

1. AIDS — The First 20 Years

2. In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

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4. Molecular basis of human immunodeficiency virus drug resistance: An update

5. Patterns of primary antiretroviral drug resistance in antiretroviral-naive HIV-1-infected individuals in a midwest university clinic

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