Synthesis, Pharmacological and Biophysical Characterization, and Membrane-Interaction QSAR Analysis of Cationic Amphiphilic Model Compounds-Reference-Cited by-同舟云学术

Synthesis, Pharmacological and Biophysical Characterization, and Membrane-Interaction QSAR Analysis of Cationic Amphiphilic Model Compounds

Published:1999-08-26 Issue:19 Volume:42 Page:3874-3888
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Klein Christian D. P.¹,Klingmüller Martin¹,Schellinski Christiane¹,Landmann Silke¹,Hauschild Stefanie¹,Heber Dieter¹,Mohr Klaus¹,Hopfinger A. J.¹

Affiliation:

1. Laboratory of Molecular Modeling and Design, M/C 781, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612-7231, Department of Pharmaceutical Chemistry, Pharmaceutical Institute, University of Kiel, Gutenbergstrasse 76, D-24118 Kiel, Germany, and Department of Pharmacology and Toxicology, Pharmaceutical Institute, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm980694a

Reference49 articles.

1. Comparison between the activities of cationic amphiphilic drugs to affect phospholipid-membranes and to depress cardiac function

2. Ca replacement by cationic amphiphilic drugs from lipid monolayers

3. The ability of cationic amphiphilic compounds to depress the transition temperature of dipalmitoylphosphatidic acid liposomes depends on the spatial arrangement of the lipophilic moiety

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