Thalidomide Increases Human Hepatic Cytochrome P450 3A Enzymes by Direct Activation of the Pregnane X Receptor-Reference-Cited by-同舟云学术

Thalidomide Increases Human Hepatic Cytochrome P450 3A Enzymes by Direct Activation of the Pregnane X Receptor

Published:2014-02-05 Issue:2 Volume:27 Page:304-308
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Murayama Norie¹,van Beuningen Rinie²,Suemizu Hiroshi³,Guguen-Guillouzo Christiane⁴,Shibata Norio⁵,Yajima Kanako¹,Utoh Masahiro¹,Shimizu Makiko¹,Chesné Christophe⁴,Nakamura Masato³,Guengerich F. Peter⁶,Houtman René²,Yamazaki Hiroshi¹

Affiliation:

1. Showa Pharmaceutical University, 3-3165 Higashi-tamagawa Gakuen, Machida, Tokyo 194-8543, Japan

2. PamGene International, Den Bosch, The Netherlands

3. Central Institute for Experimental Animals, Kawasaki-ku, Kawasaki 210-0821, Japan

4. Biopredic International, Rennes, France

5. Nagoya Institute of Technology, Showa-ku, Nagoya 466-8555, Japan

6. Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, United States

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx4004374

Reference20 articles.

1. THALIDOMIDE AND CONGENITAL ABNORMALITIES

2. Thalidomide for treatment of multiple myeloma: 10 years later

3. Clinical Evidence of Pharmacokinetic Changes in Thalidomide Therapy

4. Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity

5. Thalidomide as a Possible Biological Acylating Agent

Cited by 24 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. In Vivo and In Vitro Induction of Cytochrome P450 3A4 by Thalidomide in Humanized-Liver Mice and Experimental Human Hepatocyte HepaSH cells;Chemical Research in Toxicology;2024-04-16

2. Species Specificity and Selection of Models for Drug Oxidations Mediated by Polymorphic Human Enzymes;Drug Metabolism and Disposition;2022-06-30

3. Computational Investigation of the Bisphenolic Drug Metabolism by Cytochrome P450: What Factors Favor Intramolecular Phenol Coupling;Chemical Research in Toxicology;2022-03-01

4. Searching for Constitutive Androstane Receptor Modulators;Drug Metabolism and Disposition;2022-02-19

5. Synthesis of novel thiazolidinic-phthalimide derivatives evaluated as new multi-target antiepileptic agents;Bioorganic Chemistry;2022-02