Discovery of ((S)-5-(Methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone As a Potent and Selective IKur Inhibitor-Reference-Cited by-同舟云学术

Discovery of ((S)-5-(Methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone As a Potent and Selective IKur Inhibitor

Published:2012-03-21 Issue:7 Volume:55 Page:3036-3048
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Finlay Heather J.¹,Lloyd John¹,Vaccaro Wayne¹,Kover Alexander¹,Yan Lin¹,Bhave Gauri¹,Prol Joseph¹,Huynh Tram¹,Bhandaru Rao¹,Caringal Yolanda¹,DiMarco John¹,Gan Jinping¹,Harper Tim¹,Huang Christine¹,Conder Mary Lee¹,Sun Huabin¹,Levesque Paul¹,Blanar Michael¹,Atwal Karnail¹,Wexler Ruth¹

Affiliation:

1. Departments of Discovery Chemistry, ‡Crystallography, §Biology and ∥Preclinical Candidate Optimization, Bristol-Myers Squibb, Research and Development, P.O. Box 5400, Princeton, New Jersey 08543-5400, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201386u

Reference24 articles.

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