Design, Synthesis, and Evaluation of Orally Active 4-(2,4-Difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2,1-f][1,2,4]triazines as Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Inhibitors-Reference-Cited by-同舟云学术

Design, Synthesis, and Evaluation of Orally Active 4-(2,4-Difluoro-5-(methoxycarbamoyl)phenylamino)pyrrolo[2,1-f][1,2,4]triazines as Dual Vascular Endothelial Growth Factor Receptor-2 and Fibroblast Growth Factor Receptor-1 Inhibitors

Published:2005-05-17 Issue:12 Volume:48 Page:3991-4008
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Borzilleri Robert M.¹,Zheng Xiaoping¹,Qian Ligang¹,Ellis Christopher¹,Cai Zhen-wei¹,Wautlet Barri S.¹,Mortillo Steve¹,Jeyaseelan, Robert¹,Kukral Daniel W.¹,Fura Aberra¹,Kamath Amrita¹,Vyas Viral¹,Tokarski John S.¹,Barrish Joel C.¹,Hunt John T.¹,Lombardo Louis J.¹,Fargnoli Joseph¹,Bhide Rajeev S.¹

Affiliation:

1. Departments of Oncology Chemistry, Discovery Biology, Metabolism and Pharmacokinetics, and Structural Biology and Modeling, Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 4000, Princeton, New Jersey 08543-4000

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0501275

Reference77 articles.

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