Mechanism of Enantioseparation of Salsolinols, Endogenous Neurotoxins in Human Brain, with Ion-Pair Chromatography Using β-Cyclodextrin as a Mobile Phase Additive-Reference-Cited by-同舟云学术

Mechanism of Enantioseparation of Salsolinols, Endogenous Neurotoxins in Human Brain, with Ion-Pair Chromatography Using β-Cyclodextrin as a Mobile Phase Additive

Published:1996-09-01 Issue:17 Volume:68 Page:2826-2831
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Deng Yulin¹,Maruyama Wakako¹,Yamamura Hatsuo¹,Kawai Masao¹,Dostert Philippe¹,Naoi Makoto¹

Affiliation:

1. Departments of Applied Chemistry and Biosciences, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya, Japan, Laboratory of Biochemistry and Metabolism, Department of Basic Gerontorlogy, National Institute for Longevity Sciences, Obu, Japan, and Research and Development, Pharmacia-Upjohn, Milan, Italy

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ac960185l

Reference24 articles.

1. Dopamine-derived endogenous 1(R),2(N)-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, N-methyl-(R)-salsolinol, induced parkinsonism in rat: biochemical, pathological and behavioral studies

2. N-Methylation of Dopamine-Derived 6,7-Dihydroxy-1,2,3,4-Tetrahydroisoquinoline, (R)-Salsolinol, in Rat Brains: In Vivo Microdialysis Study

3. Presence of 2-methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline and 1,2-dimethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, novel endogenous amines, in parkinsonian and normal human brains

4. Pharmacologic activity of stereoisomers of 1-substituted 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines: Inhibition of 3H-dopamine accumulation by rat brain slices and lipolytic activity with isolated mouse fat cells

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