Synthesis and Radioligand Binding Studies of Bis-isoquinolinium Derivatives as Small Conductance Ca2+-Activated K+ Channel Blockers-Reference-Cited by-同舟云学术

Synthesis and Radioligand Binding Studies of Bis-isoquinolinium Derivatives as Small Conductance Ca2+-Activated K+ Channel Blockers

Published:2007-09-15 Issue:21 Volume:50 Page:5070-5075
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Graulich Amaury¹,Dilly Sébastien¹,Farce Amaury¹,Scuvée-Moreau Jacqueline¹,Waroux Olivier¹,Lamy Cédric¹,Chavatte Philippe¹,Seutin Vincent¹,Liégeois Jean-François¹

Affiliation:

1. Laboratory of Medicinal Chemistry, Drug Research Center, University of Liège, Avenue de l'Hôpital, 1 (B36), B-4000 Liège 1, Belgium, Laboratory of Pharmacology, Research Center for Cellular and Molecular Neurobiology, University of Liège, Avenue de l'Hôpital, 1 (B36), B-4000 Liège 1, Belgium, and Faculté des Sciences Pharmaceutiques et Biologiques, Laboratoire de Chimie Thérapeutique, EA 1043, 3, Rue du Professeur Laguesse, BP 83, 59006 Lille Cedex, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070412j

Reference31 articles.

1. A Cyclin-Dependent Kinase-Activating Kinase (CAK) in Budding Yeast Unrelated to Vertebrate CAK

2. An apamin-sensitive Ca2+-activated K+ current in hippocampal pyramidal neurons

3. Differential Distribution of Three Ca2+-Activated K+ Channel Subunits, SK1, SK2, and SK3, in the Adult Rat Central Nervous System

4. Effect of apamin, a toxin that inhibits Ca2+-dependent K+ channels, on learning and memory processes

5. Apamin improves learning in an object recognition task in rats

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