Structure-Directed Reversion in the π-Facial Stereoselective Alkylation of Chiral Bicyclic Lactams

Author:

Soteras Ignacio1,Lozano Oscar1,Escolano Carmen1,Orozco Modesto1,Amat Mercedes1,Bosch Joan1,Luque F. Javier1

Affiliation:

1. Department of Physical Chemistry and Laboratory of Organic Chemistry, Faculty of Pharmacy, and Institute of Biomedicine (IBUB), University of Barcelona, 08028 Barcelona, Spain, Molecular Modeling and Bioinformatics Unit, Institute of Biomedical Research, Barcelona Scientific Park, 08028 Barcelona, Spain, Department of Life Sciences, Barcelona Supercomputing Centre, 08034 Barcelona, Spain, and Department of Biochemistry, Faculty of Biology, University of Barcelona, Barcelona 08028, Spain

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference70 articles.

1. Högberg, H.E.InStereoselective Synthesis, Methods of Organic Chemistry (Houben-Weyl);Helmchen, G., Hoffman, R. W., Mulzer, J., Schaumann, E., Eds.Thieme:Stuttgart, 1996; E21,Vol. 2, pp791−915

2. For reviews, see:

3. Chiral non-racemic bicyclic lactams. Vehicles for the construction of natural and unnatural products containing quaternary carbon centers.

4. bMeyers, A. I.InStereocontrolled Organic Synthesis;Blackwell Scientific Publications:Oxford, 1994; pp145−175

5. Chiral bicyclic lactams: useful precursors and templates for asymmetric syntheses1

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