New Potent Antihyperglycemic Agents in db/db Mice: Synthesis and Structure−Activity Relationship Studies of (4-Substituted benzyl)(trifluoromethyl)pyrazoles and -pyrazolones-Reference-Cited by-同舟云学术

New Potent Antihyperglycemic Agents in db/db Mice: Synthesis and Structure−Activity Relationship Studies of (4-Substituted benzyl)(trifluoromethyl)pyrazoles and -pyrazolones

Published:1996-01-01 Issue:20 Volume:39 Page:3920-3928
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kees Kenneth L.¹,Fitzgerald, John J.¹,Steiner Kurt E.¹,Mattes James F.¹,Mihan Brenda¹,Tosi Theresa¹,Mondoro Diane¹,McCaleb Michael L.¹

Affiliation:

1. Departments of Medicinal Chemistry and Analytical Chemistry, Global Chemical Sciences, and Cardiovascular and Metabolic Diseases Pharmacology, Wyeth-Ayerst Research, Princeton, New Jersey 08543-8000

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm960444z

Reference9 articles.

1. van der Waals radii for sulfur and half-thickness of a phenyl ring are 1.85 Å; see: Cotton, F. A.; Wilkinson, G.Advanced Inorganic Chemistry, 3rd ed.; Interscience: New York, 1972; p 120.

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