1. Institute for Protein Research, Osaka University, and CREST, Japan Science and Technology Agency, Yamadaoka 3-2, Suita, Osaka 565-0871, Japan, National Institute of Advanced Industrial Science and Technology, Midorigaoka 1-8-31, Ikeda, Osaka 563-8577, Japan, and Department of Pathological Sciences, Faculty of Medical Sciences, University of Fukui, and CREST, Japan Science and Technology Agency, Eiheiji, Fukui 910-1193, Japan