Dual-Action Lipophilic Iminosugar Improves Glycemic Control in Obese Rodents by Reduction of Visceral Glycosphingolipids and Buffering of Carbohydrate Assimilation-Reference-Cited by-同舟云学术

Dual-Action Lipophilic Iminosugar Improves Glycemic Control in Obese Rodents by Reduction of Visceral Glycosphingolipids and Buffering of Carbohydrate Assimilation

Published:2009-12-14 Issue:2 Volume:53 Page:689-698
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wennekes Tom¹,Meijer Alfred J.²,Groen Albert K.²,Boot Rolf G.²,Groener Johanna E.²,van Eijk Marco²,Ottenhoff Roelof²,Bijl Nora²,Ghauharali Karen²,Song Hang¹,O’Shea Tom J.³,Liu Hanlan³,Yew Nelson³,Copeland Diane³,van den Berg Richard J.¹,van der Marel Gijsbert A.¹,Overkleeft Herman S.¹,Aerts Johannes M.²

Affiliation:

1. Gorlaeus Laboratories, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands

2. Department of Medical Biochemistry, Academic Medical Center, Amsterdam, The Netherlands

3. Drug and Biomaterial R&D, Genzyme, Waltham, Massachusetts

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901281m

Reference40 articles.

1. Minireview: Weapons of Lean Body Mass Destruction: The Role of Ectopic Lipids in the Metabolic Syndrome