Design, Synthesis, and Pharmacological Profile of Novel Fused Pyrazolo[4,3-d]pyridine and Pyrazolo[3,4-b][1,8]naphthyridine Isosteres: A New Class of Potent and Selective Acetylcholinesterase Inhibitors-Reference-Cited by-同舟云学术

Design, Synthesis, and Pharmacological Profile of Novel Fused Pyrazolo[4,3-d]pyridine and Pyrazolo[3,4-b][1,8]naphthyridine Isosteres: A New Class of Potent and Selective Acetylcholinesterase Inhibitors

Published:2003-02-28 Issue:7 Volume:46 Page:1144-1152
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Barreiro Eliezer J.¹,Camara Celso A.¹,Verli Hugo¹,Brazil-Más Leonora¹,Castro Newton G.¹,Cintra Wagner M.¹,Aracava Yasco¹,Rodrigues Carlos R.¹,Fraga Carlos A. M.¹

Affiliation:

1. Laboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio), Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, C. P. 68.006, 21944-910, Rio de Janeiro, RJ, Brazil, Departamento de Química Orgânica, Instituto de Química, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil, and Departamento de Farmacologia Básica e Clínica, Instituto de Ciências Biomédicas, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm020391n

Reference34 articles.

1. The Pharmacotherapy of Alzheimer's Disease Based on the Cholinergic Hypothesis: an Update

2. Cholinergic receptors and neurodegenerative diseases

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