Asymmetric Synthesis of a Glucagon Receptor Antagonist via Friedel–Crafts Alkylation of Indole with Chiral α-Phenyl Benzyl Cation-Reference-Cited by-同舟云学术

Asymmetric Synthesis of a Glucagon Receptor Antagonist via Friedel–Crafts Alkylation of Indole with Chiral α-Phenyl Benzyl Cation

Published:2012-10-26 Issue:11 Volume:16 Page:1832-1845
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Chung John Y. L.¹,Steinhuebel Dietrich¹,Krska Shane W.¹,Hartner Fred W.¹,Cai Chaoxian¹,Rosen Jonathan¹,Mancheno Danny E.¹,Pei Tao¹,DiMichele Lisa¹,Ball Richard G.¹,Chen Cheng-yi¹,Tan Lushi¹,Alorati Antony D.²,Brewer Sarah E.²,Scott Jeremy P.²

Affiliation:

1. Process Chemistry, Merck Research Laboratories, Rahway, New Jersey 07065, United States

2. Process Research Preparative Laboratory, Merck Sharp & Dohme Research Laboratories, Hertford Road, Hoddesdon, Hertfordshire EN11 9BU, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op300249q

Reference44 articles.

1. Global and societal implications of the diabetes epidemic

2. An Update on the Etiology and Epidemiology of Diabetes Mellitus

3. Medicinal Chemistry of Drugs Used in Diabetic Cardiomyopathy

4. Sitagliptin

5. DPP4 Inhibitors: a new approach in diabetes treatment

Cited by 33 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Cobalt-Catalyzed Enantioconvergent Negishi Cross-Coupling of α-Bromoketones;Journal of the American Chemical Society;2023-10-31

2. Enantioselective Transformations in the Synthesis of Therapeutic Agents;Chemical Reviews;2023-07-07

3. The Two Faces of Carbenium Ions: Intermolecular Trapping of Prochiral Carbocations with Stereocontrol;Israel Journal of Chemistry;2023-05-22

4. Biomimetic Total Synthesis and the Biological Evaluation of Natural Product (−)-Fargesone A as a Novel FXR Agonist;JACS Au;2022-12-07

5. Hierarchical Catalysts Prepared by Interzeolite Transformation;Journal of the American Chemical Society;2022-03-10