Novel Synthesis of the Hexahydroimidazo[1,5b]isoquinoline Scaffold: Application to the Synthesis of Glucocorticoid Receptor Modulators-Reference-Cited by-同舟云学术

Novel Synthesis of the Hexahydroimidazo[1,5b]isoquinoline Scaffold: Application to the Synthesis of Glucocorticoid Receptor Modulators

Published:2010-01-04 Issue:3 Volume:53 Page:1270-1280
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Xiao Hai-Yun¹,Wu Dauh-Rurng¹,Malley Mary F.¹,Gougoutas Jack Z.¹,Habte Sium F.¹,Cunningham Mark D.¹,Somerville John E.¹,Dodd John H.¹,Barrish Joel C.¹,Nadler Steven G.¹,Dhar T. G. Murali¹

Affiliation:

1. Bristol-Myers Squibb Company, Research and Development, Princeton, New Jersey 08543-4000

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm901551w

Reference27 articles.

1. Effects of glucocorticoids on gene transcription

2. A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

3. Role of CBP/P300 in nuclear receptor signalling

4. DNA Binding of the Glucocorticoid Receptor Is Not Essential for Survival

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