Drug Delivery Systems Based on Trimethyl Lock Lactonization: Poly(ethylene glycol) Prodrugs of Amino-Containing Compounds
Author:
Affiliation:
1. Enzon, Inc., 20 Kingsbridge Road, Piscataway, New Jersey 08854
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm990498j
Reference41 articles.
1. Correlation of reaction rate acceleration with rotational restriction. Crystal-structure analysis of compounds with a trialkyl lock
2. Steric acceleration of lactonization reaction: an analysis of "stereopopulation control"
3. Comparison of stereopopulation control with conventional steric effects in lactonization of hydrocoumarinic acids
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