Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors-Reference-Cited by-同舟云学术

Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors

Published:2015-06-01 Issue:7 Volume:6 Page:787-792
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Wang Yonghui¹,Cai Wei²,Cheng Yaobang²,Yang Ting²,Liu Qian²,Zhang Guifeng²,Meng Qinghua²,Han Fangbin²,Huang Yafei¹,Zhou Ling²,Xiang Zhijun²,Zhao Yong-Gang²,Xu Yan²,Cheng Ziqiang²,Lu Sijie²,Wu Qianqian²,Xiang Jia-Ning²,Elliott John D.²,Leung Stewart²,Ren Feng²,Lin Xichen²

Affiliation:

1. School of Pharmacy, Fudan University, 826 Zhangheng Road, Pudong, Shanghai 201203, China

2. Research and Development, GlaxoSmithKline, No. 3 Building, 898 Halei Road, Pudong, Shanghai 201203, China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.5b00122

Reference37 articles.

1. Role of Th1 and Th17 cells in organ-specific autoimmunity

2. IL-17 Plays an Important Role in the Development of Experimental Autoimmune Encephalomyelitis