Inhibition of Invasion in Pancreatic Cancer Cells by Conjugate of EPA with β3,3-Pip-OH via PI3K/Akt/NF-kB Pathway

Author:

Amin Hina1,Wani Naiem Ahmad,Farooq Saleem,Nayak Debasis1,Chakraborty Souneek1,Shankar Sudha,Rasool Reyaz ur1,Koul Surinder,Goswami Anindya1,Rai Rajkishor

Affiliation:

1. Cancer Pharmacology Division, ‡Medicinal Chemistry Division, and §Bioorganic Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, J&K 180001, India

Funder

Council for Scientific and Industrial Research

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference24 articles.

1. Cancer statistics, 2014

2. Matrisian, L. M.; Aizenberg, R.; Rosenzweig, A.The alarming rise of pancreatic cancer deaths in the United States: Why we need to stem the tide today.Pancreatic Cancer Action Network, Manhattan Beach, CA, 2012

3. Therapeutic Potential of Curcumin Derived from Turmeric (Curcuma longa)

4. Role of NF-κB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death

5. Mitogenic and antiapoptotic role of constitutive NF-?B/Rel activity in pancreatic cancer

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