Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor-Reference-Cited by-同舟云学术

Discovery of MK-8831, A Novel Spiro-Proline Macrocycle as a Pan-Genotypic HCV-NS3/4a Protease Inhibitor

Published:2015-12-23 Issue:1 Volume:7 Page:111-116
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Neelamkavil Santhosh F.¹,Agrawal Sony¹,Bara Thomas¹,Bennett Chad¹,Bhat Sathesh¹,Biswas Dipshikha¹,Brockunier Linda¹,Buist Nicole¹,Burnette Duane¹,Cartwright Mark¹,Chackalamannil Samuel¹,Chase Robert¹,Chelliah Mariappan¹,Chen Austin¹,Clasby Martin¹,Colandrea Vincent J.¹,Davies Ian W.¹,Eagen Keith¹,Guo Zhuyan¹,Han Yongxin¹,Howe John¹,Jayne Charles¹,Josien Hubert¹,Kargman Stacia¹,Marcantonio Karen¹,Miao Shouwu¹,Miller Randy¹,Nolting Andrew¹,Pinto Patrick¹,Rajagopalan Murali¹,Ruck Rebecca T.¹,Shah Unmesh¹,Soriano Aileen¹,Sperbeck Donald¹,Velazquez Francisco¹,Wu Jin¹,Xia Yan¹,Venkatraman Srikanth¹

Affiliation:

1. Merck Research Laboratories, Kenilworth, New Jersey 07033, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.5b00425

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