Structure–Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97-Reference-Cited by-同舟云学术

Structure–Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97

Published:2015-10-23 Issue:12 Volume:6 Page:1225-1230
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Alverez Celeste¹²,Arkin Michelle R.³,Bulfer Stacie L.³,Colombo Raffaele²,Kovaliov Marina²,LaPorte Matthew G.²,Lim Chaemin²,Liang Mary²,Moore William J.⁴,Neitz R. Jeffrey³,Yan Yongzhao²,Yue Zhizhou²,Huryn Donna M.¹²,Wipf Peter¹²

Affiliation:

1. Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States

2. Chemical Diversity Center, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States

3. Department of Pharmaceutical Chemistry, Small Molecule Discovery Center, University of California, San Francisco, California 94158, United States

4. Leidos Biomedical Research, Inc., Frederick, Maryland 21702, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.5b00364

Reference46 articles.

1. Applications of Fluorine in Medicinal Chemistry

2. The Electrical Effect of the Sulfur Pentafluoride Group

3. A New Method for the Synthesis of Aromatic Sulfurpentafluorides and Studies of the Stability of the Sulfurpentafluoride Group in Common Synthetic Transformations

4. Preparation and Utility of Organic Pentafluorosulfanyl-Containing Compounds

5. Synthetic chemistry and biological activity of pentafluorosulphanyl (SF5) organic molecules

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