Antagonism/Agonism Modulation to Build Novel Antihypertensives Selectively Triggering I1-Imidazoline Receptor Activation

Author:

Del Bello Fabio1,Bargelli Valentina2,Cifani Carlo3,Gratteri Paola4,Bazzicalupi Carla5,Diamanti Eleonora1,Giannella Mario1,Mammoli Valerio1,Matucci Rosanna2,Micioni Di Bonaventura Maria Vittoria3,Piergentili Alessandro1,Quaglia Wilma1,Pigini Maria1

Affiliation:

1. School of Pharmacy, Medicinal Chemistry Unit, University of Camerino, Via S. Agostino 1, 62032 Camerino, Italy

2. Department NEUROFARBA, Preclinical and Clinical Pharmacology, University of Firenze, Viale Pieraccini 6, 50139 Firenze, Italy

3. School of Pharmacy, Pharmacology Unit, University of Camerino, Via Madonna delle Carceri 9, 62032 Camerino, Italy

4. Department NEUROFARBA, Pharmaceutical and Nutraceutical Section and Laboratory of Molecular Modeling Cheminformatics & QSAR, University of Firenze, via Ugo Schiff 6, 50019 Sesto Fiorentino, Firenze, Italy

5. Department of Chemistry Ugo Schiff, University of Firenze, Via della Lastruccia 3, 50019 Sesto Fiorentino, Italy

Funder

Antica Farmacia Peroni

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

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