Identification of Slow-Binding Inhibitors of the BoNT/A Protease-Reference-Cited by-同舟云学术

Identification of Slow-Binding Inhibitors of the BoNT/A Protease

Published:2022-03-08 Issue:4 Volume:13 Page:742-747
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Patel Ealin N.¹^ORCID,Turner Lewis D.¹²^ORCID,Hixon Mark S.¹,Janda Kim D.¹^ORCID

Affiliation:

1. Departments of Chemistry and Immunology, The Skaggs Institute for Chemical Biology, Worm Institute of Research and Medicine (WIRM), The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States

2. Biosplice Therapeutics, 9360 Towne Centre Drive, San Diego, California 92121, United States

Funder

Division of Intramural Research, National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.2c00028

Reference49 articles.

1. Recent developments in clinical trials of botulinum neurotoxins

2. Properties and use of botulinum toxin and other microbial neurotoxins in medicine

3. Botulinum Toxin as a Biological Weapon

4. Equine antitoxin use and other factors that predict outcome in type A foodborne botulism

5. Identification of a calcium-dependent matrix metalloproteinase complex in rat chorioallantoid membranes during labour

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1. A novel RRGW derived peptide is a promising inhibitor of BoNT/A;Journal of Enzyme Inhibition and Medicinal Chemistry;2023-04-27

2. Investigation of Salicylanilides as Botulinum Toxin Antagonists;ACS Infectious Diseases;2022-07-25