A New Naphthopyran Derivative Combines <i>c</i>-Myb Inhibition, Microtubule-Targeting Effects, and Antiangiogenic Properties-Reference-Cited by-同舟云学术

A New Naphthopyran Derivative Combines c-Myb Inhibition, Microtubule-Targeting Effects, and Antiangiogenic Properties

Published:2022-10-31 Issue:11 Volume:13 Page:1783-1790
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Köhler Leonhard H. F.¹,Reich Sebastian¹,Yusenko Maria²,Klempnauer Karl-Heinz²^ORCID,Shaikh Amin H.³,Ahmed Khursheed³,Begemann Gerrit⁴,Schobert Rainer¹^ORCID,Biersack Bernhard¹^ORCID

Affiliation:

1. Organic Chemistry Laboratory, University of Bayreuth, Universitätsstrasse 30, 95440 Bayreuth, Germany

2. Institute for Biochemistry, Westfälische-Wilhelms-Universität, Wilhelm-Klemm-Strasse 2, 48149 Münster, Germany

3. Department of Chemistry & Post Graduate Research Center, Abeda Inamdar Senior College, Camp, Pune 411001, India

4. Developmental Biology, University of Bayreuth, Universitätsstrasse 30, 95440 Bayreuth, Germany

Funder

Wilhelm Sander-Stiftung

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.2c00403

Reference40 articles.

1. MYB function in normal and cancer cells

2. Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of c-Myb

3. An oligomer complementary to c-myb-encoded mRNA inhibits proliferation of human myeloid leukemia cell lines.

4. Normal and leukemic hematopoietic cells manifest differential sensitivity to inhibitory effects of c-myb antisense oligodeoxynucleotides: an in vitro study relevant to bone marrow purging.

5. c-Myb and Bcl-x Overexpression Predicts Poor Prognosis in Colorectal Cancer

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