5-Oxopyrrolidine-3-carboxamides as Nav1.8 Inhibitors for Treating Pain Disorders, Cough Disorders, and Acute and Chronic Itch Disorders
Author:
Affiliation:
1. Smith, Gambrell & Russell LLP, 1105 West Peachtree Street NE, Suite 1000, Atlanta, Georgia 30309, United States
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.2c00144
Reference6 articles.
1. Epigenetic Mechanisms of Neural Plasticity in Chronic Neuropathic Pain
2. Novel Approaches, Drug Candidates, and Targets in Pain Drug Discovery
3. Pain behavior in SCN9A (Nav1.7) and SCN10A (Nav1.8) mutant rodent models
4. Painful diabetic peripheral neuropathy: Role of oxidative stress and central sensitisation
5. Ventricular voltage‐gated ion channels: Detection, characteristics, mechanisms, and drug safety evaluation
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1. The pursuit of accurate predictive models of the bioactivity of small molecules;Chemical Science;2024
2. Nitrogen-Containing 2,3-Dihydroquinazolinone Compounds as Nav1.8 Inhibitors for Treating Pain and Cardiovascular Diseases;ACS Medicinal Chemistry Letters;2023-06-09
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